Essent Biologics’ scaffold materials are human ECM-derived biomaterials that cause desirable cellular interactions and contribute to the formation of new functional tissues for medical purposes.

Extracellular matrices (ECM) are a three-dimensional network of proteins, enzymes, glycosaminoglycans and other macromolecules that provide scaffolding for surrounding cells through structural and biochemical support.

Scaffold materials are critical for cell adhesion, signaling, migration, differentiation, forming boundaries between different tissues and organs and transducing mechanical signals.

key applications

Cell-based Therapies

iPSCs, Bioreactors

Spheroids

Tissue Spheroids, Organoids, Assembloids

Drug Discovery & Development

Toxicology Screening, Drug Target Validation

Microfluidic Chips

Tissues, Organs, and Labs-on-a-chip

Tissue Engineering

3D Bioprinting, Decell/Recell

Biomaterials

Scaffolds, Growth Factors

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know your source

Our scaffold materials are derived from donated human tissue. Tissue donation represents a gift from the donor and the donor family.

All potential tissue donors undergo a comprehensive screening that includes a physical assessment, medical history and social risk review. Tissue is recovered, and tests are performed on blood and tissue samples to screen for disease and microbiological infection. Testing includes screens for HIV, Hepatitis B and C, and syphilis.

punctuate your research

Identify which ECM conditions are best for your cell adhesion, proliferation or differentiation study

Realize homogeneous and reproducible results because our scaffolds have predictable mechanical properties and are manufactured under GMP requirements

Elevate your processes because our scaffolds are biodegradable and allow host cells, over time, to produce their own extracellular matrix and replace the degraded scaffold