Essent Biologics’ scaffold materials are human ECM-derived biomaterials that cause desirable cellular interactions and contribute to the formation of new functional tissues for medical purposes.
Extracellular matrices (ECM) are a three-dimensional network of proteins, enzymes, glycosaminoglycans and other macromolecules that provide scaffolding for surrounding cells through structural and biochemical support.
Scaffold materials are critical for cell adhesion, signaling, migration, differentiation, forming boundaries between different tissues and organs and transducing mechanical signals.
key applications
Cell-based Therapies
Encapsulation, Microcarriers, Controlled Degradation
Spheroids
Tissue Spheroids, Organoids, Assembloids
Drug Discovery & Development
Microspheres, Fillers, Drug Target Validation
Microfluidic Chips
Tissues-/Organs-/ body-on-a-chip, Toxicology Screening
Tissue Engineering
3D Bioprinting, Electrospinning, 3D Hydrogels, Tunable Scaffolds
cell adhesion / biocompatibility
Cultureware and Device Coating, Biorelevant Additive, Wound Dressing
remove
your limits
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know your source
Our scaffold materials are derived from donated human tissue. Tissue donation represents a gift from the donor and the donor family.
All potential tissue donors undergo a comprehensive screening that includes a physical assessment, medical history and social risk review. Tissue is recovered, and tests are performed on blood and tissue samples to screen for disease and microbiological infection. Testing includes screens for HIV, Hepatitis B and C, and syphilis.
