Human Native Tissue-Derived Type I Collagen
As the main structural protein in the human body, native Type I Collagen is crucial to a vast array of medical and scientific research, providing structure to 3D scaffolds and an ideal ex-vivo environment for the attachment, proliferation, differentiation, and migration of cells.
Type I Collagen’s inherent self-organizing capacity, gel-forming characteristics, and abundant cell and matrix interaction domains make it ideal for two- and three-dimensional cell culture, labware coating applications, drug delivery, bioprinting, and as a scaffold for myriad tissue engineering modalities.
In molecular form, Type I Collagen has a triple helical conformation consisting of two genetically distinct alpha chains. The chains are generally composed of an amino acid sequence of Gly-X-Y where X and Y frequently are proline and hydroxyproline. The terminal domains of the collagen molecule are called telopeptides and these regions can be cleaved with proteolytic enzymes such as pepsin. When the telopeptides have been cleaved, the collagen is referred to as atelocollagen.
Please contact info@essentbiologics.org or call 855.953.CELL to inquire about product availability.
PRICE:
Essent’s Native Tissue-Derived Type I Collagen is optimal for many cell and tissue engineering applications because it has undergone the natural extracellular post-translational modifications and interacted with other biomolecules from the matrisome.
Essent Type I Human Atelocollagen is isolated from the dermis of consenting tissue donors aged 18-30 years old. Essent manufacturing occurs in a qualified GMP-compliant facility and each product lot is evaluated for purity, identity, functionality, sterility and endotoxin.
- Purified protein derived from human dermis
- Comprehensive donor data available upon request
- 20mL of 3-8mg/mL bottled in 30mL bottles
- This product is for research use only or for further manufacturing
- Essent’s Type I Atelocollagen is produced to a purity ranging from 95%, and to concentrations ranging between 3mg/mL and 8mg/mL.
- Storage: 2-8 ⁰C
- Shipped In: Shipping box with wet ice
Human Native Tissue-Derived Type I Collagen
